Concentrating on minimizing the development of drug-tolerance versus withdraw.

For those who wish to concentrate their charitable efforts on the treatment of the demand side of drug addiction (speaking in the direction of charity, not regulatory force), why not concentrate on minimizing the development of drug-tolerance versus withdraw. Thus, if individuals must continue to increase dosages due to a natural build-up in tolerance why not concentrate efforts toward decreases tolerance to the point that extremely small amount have large effects? I personally have no desire to curve someones addictions, but if one did, do you think this is a good apprach?

Thoughts? Criticism?